fa توزیع فراوانی ژنهای کد کننده فیمبریه در E.coliجداشده از بیماران مبتلا به عفونت دستگاه ادراری Abstract Bachground and objectives: The ability of adherence to the surface of host cell is very critical in the colonization of microbial pathogens. It has been revealed that E. coli strains that infect urinary tracts have different fimbrea such as I, S, FIC, Dr, and fimbrial adhesions. Material and Methods: In this study, 363 urine samples were obtained from patients with urinary tract infections reffered to clinical laboratories in Western areas of Tehran ,2008-2010 by using biochemical tests,200 samples were confirmed to be E.coli.First, DNA was extracted by boiling method and then the presence of fimbria fim, sfa, pap, foc, and afa genes tested by PCR. Results: In 200 samples, the frequency of fimbria fim, sfa, pap, foc, and afa genes are188 (%94 ), 34 (%17), 20 (%10), 61 (%31) and 71 (%35.5), respectively. Conclusion: The resultes show that FIM ans SFA are the most fimbrial genes of E. coli isolated from urine samples .This information can be valuable in etiology of urinary tract infection (UTI), UTI administration, and making of new vaccines. Key words: Urinary tract infection, fimbria, Uropathogenic E. coli (UPEC) Key words: Urinary tract infection, fimbria, Uropathogenic E. coli (UPEC) 31 37 http://mlj.goums.ac.ir/browse.php?a_code=A-10-1-80&slc_lang=fa&sid=1 A Nazemi علی ناظمی alinazemy@yahoo.com 100319475328460013332 100319475328460013332 Yes Assistant professor, Department of Biology, دانشگاه آزاد اسلامی واحد تنکابن M Naderi مهسا نادری 100319475328460013333 100319475328460013333 No دانشگاه آزاد اسلامی واحد تنکابن M Jafarpour مصطفی جعفرپور 100319475328460013334 100319475328460013334 No دانشگاه آزاد اسلامی واحد تنکابن M Mirinargesi میرساعد میری نرگسی 100319475328460013335 100319475328460013335 No دانشگاه آزاد اسلامی واحد تنکابن SH Sharifi شهرآشوب شریفی 100319475328460013336 100319475328460013336 No دانشگاه آنکارا ، ترکیه