fa شیوع عفونت کلبسیلایی در بیمارستان 5 آذر گرگان (سال 1390) تحقيقي Original Paper Abstract Background and Objective: Klebsiella pneumoniae is one of the agents causing nosocomial infection therefore, we decided to report the prevalence of Klebsiella pneumoniae caused infection. Material and methods: The frequency of Klebsiella in culture media samples of Panje Azar hospital was studied in 2011-2012. After determination of the species with biochemical methods and determination of resistance to third generation cephalosporins, the existence of responsible genes for this resistance was investigated using specific primers. The PCR product for CTX-M gene was sequenced. Results: During the study, 70 isolates of Klebsiella were isolated in that 51 (72.8%) related to three months of November, December and January. Except for the one related to November, other ESBL cases belonged to these three months. Based on molecular investigation of ESBL genes, these isolates at least were in 3 types and had a high frequency in Internal, female and Emergency wards. Conclusion: The present report implied a sudden prevalence of Klebsiella pneumoniae that detected and controlled by a correct monitoring. Keyword: Klebsiella Pneumoniae, ESBL, CTX-M Klebsiella Pneumoniae, ESBL, CTX-M 43 48 http://mlj.goums.ac.ir/browse.php?a_code=A-10-1-268&slc_lang=fa&sid=1 Mahmoudjanlou, H حدیثه محمودجانلو 100319475328460012669 100319475328460012669 No Golestan University of Medical Science, Gorgan, Iran دانشگاه علوم پزشکی گلستان Ghazisaeedi, K کیومرث قاضی سعیدی 100319475328460012670 100319475328460012670 No Golestan University of Medical Science, Gorgan, Iran دانشگاه علوم پزشکی گلستان Shakeri, F فاطمه شاکری 100319475328460012671 100319475328460012671 No Payame Noor University, Gorgan, Iran مدرس دانشگاه پیام نورگلستان Ghaemi, EA عزت الله قائمی eghaemi@yahoo.com 100319475328460012672 100319475328460012672 Yes Golestan University of Medical Science, Gorgan, Iran دانشگاه علوم پزشکی گلستان