fa سطح سرمی هورمونهای تیروئیدی در تهوع و استفراغ اوایل بارداری Abstract Background and Objectives: The hyperthyroidism, caused in Pregnancy, may Leads to nausea and vomiting. The aim of this study was to establish the relationship between the serum thyroid stimulating hormone (TSH) and thyroxin. (T4), which reflect thyroid function assessment, with nausea and vomiting, among pregnant women in early pregnancy. Material and Methods: the Subjects of this Case- Control Study were the pregnant women referred to routine laboratory investigations. We Compared 60 pregnant women without nausea and Vomiting with 60 pregnant women with nausea and vomiting in Gorgan, Iran. Results: The results Show that there is an increased level of T4 among 34 subjects (56.6 %) with nausea and vomiting compared to 20 Subjects (33.3 %) of women without nausea and vomiting. The mean of T4 in Case and Control group is 11:30&plusmn;2.8 and 10.26&plusmn;2.4hg/dl. This difference is Statistically Significant. (p<0.05). TSH level is nearly the same in both groups. Conclusion: These data suggest that there is a role for elevated T4 in nausea and vomiting among pregnant women, in early pregnancy. Key words: Pregnant women, nausea and vomiting, thyroid stimulating hormone, thyroxin. Key words: Pregnant women, nausea and vomiting, thyroid stimulating hormone, thyroxin. 0 0 http://mlj.goums.ac.ir/browse.php?a_code=A-10-1-41&slc_lang=fa&sid=1 AR Mansourian آزاد رضا منصوریان azad_r_mansourian@yahoo.com 100319475328460013127 100319475328460013127 Yes Associate Professor , Biochemistry and ،دانشگاه علوم پزشکی گلستان f Shahmohammdi فرشته شاهمحمدی 100319475328460013128 100319475328460013128 No دانشگاه آزاد اسلامی تهران HR Mansourian هادی رضا منصوریان 100319475328460013129 100319475328460013129 No دانشگاه آزاد اسلامی تهران