en آسيب شناسي Pathology تحقيقي Original Paper <div style="text-align: justify;"><span style="font-size:12px;"><span style="font-family:Times New Roman;"><strong>Background and objectives:</strong> In patients with coronavirus disease 2019 (COVID-19), white blood cell (WBC) abnormalities have been found worldwide with significant inter-regional differences. In the present study, we evaluated WBC parameters concerning COVID-19 positivity and severity.<br> <strong>Methods: </strong>In this cross-sectional study, total WBC count, absolute count of each type of WBC, neutrophil to lymphocyte ratio (NLR), and lymphocyte to monocyte ratio (LMR) were compared between 150 COVID-19 patients and 150 non-COVID-19 patients presenting with COVID-19-like symptoms. Also, COVID-19 patients were divided into severe and non-severe cases.<br> <strong>Results: </strong>The severity of the disease had no significant association with age or gender (p>0.05). Total WBC count, absolute neutrophil count, absolute monocyte count, and NLR were significantly lower (p<0.05), while LMR was significantly higher in COVID-19 patients compared to non-COVID-19 patients (p<0.05). Total WBC count, absolute neutrophil count, and NLR were significantly higher (p<0.05), while absolute eosinophil count and absolute lymphocyte count were significantly lower (p<0.05) in severe COVID-19 patients compared to non-severe patients.<br> <strong>Conclusions:</strong> Age is not a predictive factor for the severity of COVID-19. Routine WBC parameters are useful in predicting the severity of the disease in COVID-19 patients and can be used as prognostic indicators. Routine WBC parameters can also be used for repeat RT-PCR testing in COVID-19 suspected patients.</span></span></div> COVID-19 Testing,Injury Severity Score,India, 1 7 http://mlj.goums.ac.ir/browse.php?a_code=A-10-1346-1&slc_lang=en&sid=1 Rajendra Zope rajendrazope2@gmail.com 100319475328460032029 100319475328460032029 No Department of Pathology, MAEER MIT Pune’s MIMER Medical College & Dr. B.S.T.R. Hospital, Talegaon Dabhade. Tal. Maval, Dist. Pune. Pin code – 410507 State – Maharashtra. Country – India Prachi Kate prachiskate@yahoo.co.in 100319475328460032030 100319475328460032030 Yes Tutor, Department of Pathology, MAEER MIT Pune’s MIMER Medical College & Dr. B.S.T.R. Hospital, Talegaon Dabhade. Janice Jaison drjanicejaison@mitmimer.com 100319475328460032031 100319475328460032031 No Department of Pathology, MAEER MIT Pune’s MIMER Medical College & Dr. B.S.T.R. Hospital, Talegaon Dabhade. Tal. Maval, Dist. Pune. Pin code – 410507 State – Maharashtra. Country – India Shalaka Saraf drshalakasaraf@gmail.com 100319475328460032032 100319475328460032032 No Department of Pathology, MAEER MIT Pune’s MIMER Medical College & Dr. B.S.T.R. Hospital, Talegaon Dabhade. Tal. Maval, Dist. Pune. Pin code – 410507 State – Maharashtra. Country – India Smita Bhide smitapbhide@gmail.com 100319475328460032033 100319475328460032033 No Department of Pathology, MAEER MIT Pune’s MIMER Medical College & Dr. B.S.T.R. Hospital, Talegaon Dabhade. Tal. Maval, Dist. Pune. Pin code – 410507 State – Maharashtra. Country – India Digant Gupta gupta.digant@gmail.com 100319475328460032034 100319475328460032034 No Department of Clinical Research and Incubation Center. MAEER MIT Pune’s MIMER Medical College & Dr. B.S.T.R. Hospital, Talegaon Dabhade. Tal. Maval, Dist. Pune. Pin code – 410507 State – Maharashtra. Country – India