Medical Laboratory Journal

en Clinico-Hematological Profile of COVID-19 Patients: A Perspective of the Indian Scenario آسيب شناسي Pathology Research Article Research Article <div style="text-align: justify;">Background: The coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2, a newly emergent coronavirus, first recognized in Wuhan, China in December 2019. Early identification of laboratory indicators helps in distinguishing severe patients from mild to moderate counterparts and can facilitate medical interventions, thereby lowering the mortality rate. The present study was done to evaluate the role of hematological parameters and basic coagulation parameters in the assessment of the severity of COVID-19. Methods: This retrospective observational study was done at a tertiary care institute from May 2020 to May 2021. Hematological and coagulation profile was studied in 200 confirmed COVID-19 cases. Data related to age, gender, and clinical features were retrieved from patients’ records. Laboratory findings such as complete blood count neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and coagulation parameters in different categories were compared. Results: The majority of patients were males (59.5%) and with mild illness (52.5%). Moderate and severe illness was present in 30% and 17.5% of cases, respectively. The frequency of anemia, leucopenia, and thrombocytopenia was 62.5%, 6%, and 5.5%, respectively. Overall neutrophilia was seen in 40.5% of cases, whereas lymphopenia was seen in 39% of cases. Coagulation parameters were also much deranged in moderate and severe cases as compared to mild cases. Conclusion: The hematopoietic and hemostatic systems are significantly affected by COVID-19. Careful evaluation of laboratory parameters assists clinicians in formulating a tailored treatment approach and in predicting disease severity.</div> COVID-19 Testing,Hematologic Tests,Blood Coagulation, 13 19 http://mlj.goums.ac.ir/browse.php?a_code=A-10-1261-1&slc_lang=en&sid=1 Iffat Jamal iffatjamal111@gmail.com 100319475328460032038 100319475328460032038 No Department of Hematology- IGIMS Patna, Patna, India Shuchi Smita shuchi.smita123@gmail.com 100319475328460032039 100319475328460032039 Yes Department of Hematology- IGIMS Patna, Patna, India Ravi Bhushan Raman bhushanravi89@yahoo.co.in 100319475328460032040 100319475328460032040 No Department of Hematology- IGIMS Patna, Patna, India Vijayanand Choudhary drvijayanandchoudhary@gmail.com 100319475328460032041 100319475328460032041 No Department of Hematology- IGIMS Patna, Patna, India Satyadeo Choubey chestsd@gmail.com 100319475328460032042 100319475328460032042 No Department of Pulmonary Medicine- IGIMS Patna, Patna, India Kaushal Kumar drkaushalkumar@yahoo.co.in 100319475328460032043 100319475328460032043 No Department of Hematology- IGIMS Patna, Patna, India